Quality of diet and mortality among Japanese men and women: Japan Public Health Center based prospective study [日本男性和女性饮食质量与死亡率的关联：日本公共卫生中心的前瞻性研究]

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BMJ 2016; 352 doi: http://dx.doi.org/10.1136/bmj.i1209 (Published 22 March 2016)
Cite this as: BMJ 2016;352:i1209

Authors
Kayo Kurotani, senior researcher, Shamima Akter, researcher, Ikuko Kashino, researcher, Atsushi Goto, assistant professor, Tetsuya Mizoue, director, Mitsuhiko Noda, director, professor, Shizuka Sasazuki, division chief, Norie Sawada, section chief, Shoichiro Tsugane, director of Research Centre for Cancer Prevention and Screening, Japan Public Health Center based Prospective Study Group

Abstract
Objective: To examine the association between adherence to the Japanese Food Guide Spinning Top and total and cause specific mortality.

Design: Large scale population based prospective cohort study in Japan with follow-up for a median of 15 years.

Setting: 11 public health centre areas across Japan.

Participants: 36 624 men and 42 970 women aged 45-75 who had no history of cancer, stroke, ischaemic heart disease, or chronic liver disease.

Main outcome measures: Deaths and causes of death identified with the residential registry and death certificates.

Results: Higher scores on the food guide (better adherence) were associated with lower total mortality; the multivariable adjusted hazard ratios (95% confidence interval) of total mortality for the lowest through highest scores were 1.00, 0.92 (0.87 to 0.97), 0.88 (0.83 to 0.93), and 0.85 (0.79 to 0.91) (P<0.001 for trend) and the multivariable adjusted hazard ratio associated with a 10 point increase in food guide scores was 0.93 (0.91 to 0.95; P<0.001 for trend). This score was inversely associated with mortality from cardiovascular disease (hazard ratio associated with a 10 point increase 0.93, 0.89 to 0.98; P=0.005 for trend) and particularly from cerebrovascular disease (0.89, 0.82 to 0.95; P=0.002 for trend). There was some evidence, though not significant, of an inverse association for cancer mortality (0.96, 0.93 to 1.00; P=0.053 for trend).

Conclusion: Closer adherence to Japanese dietary guidelines was associated with a lower risk of total mortality and mortality from cardiovascular disease, particularly from cerebrovascular disease, in Japanese adults.